Respiratory microsporidiosis caused by Enterocytozoon bieneusi in an HIV-negative hematopoietic stem cell transplant recipient
نویسندگان
چکیده
منابع مشابه
Molecular Epidemiology of Human Microsporidiosis Caused by Enterocytozoon Bieneusi
Enterocytozoon bieneusi is a common human pathogen, responsible for more than 90% of overall human microsporidian infections. The epidemiology of E. bieneusi infections, however, is not well studied, and little is known about its transmission routes. Enterocytozoon bieneusi-like spores have been reported in surface and ground water in the United States and France, and a possible outbreak of mic...
متن کاملEnterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin1
Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications of immunosuppression could be avoided when E. bieneusi is rapidly identified and fumagillin therap...
متن کاملIdentification of Enterocytozoon bieneusi spores in respiratory samples from an AIDS patient with a 2-year history of intestinal microsporidiosis.
Enterocytozoon bieneusi, a microsporidian parasite, has been recognized since 1985 as an agent of intestinal microsporidiosis leading to malabsorption syndrome, diarrhea, and weight loss in AIDS patients. Recently, however, we have identified E. bieneusi spores in the sputum, bronchoalveolar lavage, and stool samples of an AIDS patient with a 2-year history of intestinal microsporidiosis. The s...
متن کاملA new and highly divergent Enterocytozoon bieneusi genotype isolated from a renal transplant recipient.
A 49-year-old renal transplant recipient was admitted to our hospital due to abundant liquid diarrhea and dehydration. Parasitological investigations, including genotyping, led to the diagnosis of intestinal microsporidiosis due to a new and highly divergent internal transcribed spacer (ITS) genotype of Enterocytozoon bieneusi. The potential route of transmission through horse stools is discussed.
متن کاملCritical care of the hematopoietic stem cell transplant recipient.
An estimated 50,000 to 60,000 patients undergo hematopoietic stem cell transplantation (HSCT) worldwide annually, of which 15.7% are admitted to the intensive care unit (ICU). The most common reason for ICU admission is respiratory failure and almost all develop single or multiorgan failure. Most HSCT recipients admitted to ICU receive invasive mechanical ventilation (MV). The overall short-ter...
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2018
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2018.07.021